A flight from Los Angeles to Seattle was diverted to Portland late Thursday after one of the pilots lost consciousness.
Alaska Airlines said Flight 473's first officer flew the Boeing 737-700 to Portland International Airport after the captain became ill over Oregon.
The plane landed safely at 9:05 p.m. local time (12:05 a.m. ET Friday) and paramedics took the pilot to the hospital, airline spokesman Paul McElroy said.
The Seattle Times reported that a doctor on board was able to tend to the captain at the front of the plane.
There were 116 passengers and five crew members on the flight, which had been due to arrive in Seattle at 9:30 p.m. local time (12.30 a.m. ET).
The captain has been flying with Alaska Airlines for 28 years, while the first officer has been with the airline 11 years, McElroy said.
NBC station KING5?said it was not known what caused the pilot to pass out.
About 20 passengers were re-accommodated on other flights to Seattle, while the rest took a flight scheduled to land in Seattle at 1:15 a.m. local time Friday (4:15 a.m. ET).
Feb. 1, 2013 ? In a project that began with the retinal cells of nocturnal animals and has led to fundamental insights into the organization of genomic DNA, researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich show how the nuclear envelope affects nuclear architecture -- and gene regulation.
The double-stranded DNA molecules that make up the genetic material are wrapped around protein complexes to form compacted "chromatin." The active portion of the genome is less densely packed, and thus more easily accessible, than the inactive fraction, and is referred to as euchromatin. Euchromatin is typically located in the inner regions of the cell nucleus, while much of the inactive DNA in "heterochromatin" is associated with the inner face of the nuclear envelope. This type of chromatin organization is found in almost all higher organisms and may have been invented 500 million years ago.
But there is a curious exception to this generalization. In the retinal cells of nocturnal animals, the heterochromation is localized in the central area of the nucleus, as a research group led by LMU biologists Dr. Irina Solovei and Dr. Boris Joffe showed in a previous study. "This got us interested in the mechanisms that control the distribution of chromatin," says Professor Heinrich Leonhardt of LMU's Biozentrum. "How can the nuclear architecture in the rod cells of nocturnal animals be inverted in this way, and what determines the typical positioning of inactive chromatin on the outskirts of the nucleus in normal cells?" Leonhardt and his team have now completed an extensive study in search of the answers.
A fundamental principle unveiled
With the help of targeted genetic manipulations in the mouse, Joffe and Solovei together with their colleagues show for the first time that there are two independent mechanisms for fixing heterochromatin to the inner face of the nuclear envelope. These mechanisms make use of two different components of the inner nuclear membrane as clamps -- lamin A/C, and the so-called lamin-B receptor (LBR), which itself binds to B type lamins.
Normally the two components are used sequentially for this purpose. "In the course of differentiation, there is a switch from the LBR to lamin A/C, and there is always a least one type of tether available for attachment of heterochromatin to the nuclear periphery. But if both are missing, the inactive heterochromatin recoils like a severed elastic band and collapses in the center of the nucleus," explains Leonhardt. Moreover, the switch seems to be a fundamental principle of genome organization and cell differentiation in mammalian cells, as the researchers concluded from the study of 39 species and the analysis of diverse tissue types in nine genetic strains of mice.
Prospects for targeted therapies Lamin proteins not only have a structural function but also have an impact on gene regulation. Thus LBR binds B type lamins and regulates stem-cell populations by promoting the expression of genes that are important for the proliferation of rapidly dividing stem cells. The lamin A/C gene on the other hand codes for a structural component of the nuclear envelope, and regulates cellular differentiation programs like e.g. the expression of muscle-specific genes in muscle cells. Mutations in this gene result in so-called laminopathies -- rare genetic diseases that are associated with a broad spectrum of clinical symptoms, including muscular dystrophy and progeria, a premature aging syndrome.
Joffe and Solovei suspect that mutations in lamin A/C affect the expression of specific genes during the maturation and differentiation of cells, with deleterious results for their function and for tissue integrity. This notion could explain the highly diverse and complex symptoms seen in patients with mutations in the lamin A/C gene -- and it could open routes to the design of targeted therapies for laminopathies.
The new findings thus yield fundamentally new insights into how each of the many differentiated cell types in the body arises as the result of the precisely regulated expression of a specific complement of genes appropriate to each. "In the end, we have been brought from studies of night vision and an odd quirk of nature to the discovery of a fundamental regulatory mechanism: The nuclear envelope has a major say in development, and what kind of envelope our genetic material comes in makes a great deal of difference to our fate," Leonhardt concludes.
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The above story is reprinted from materials provided by Ludwig-Maximilians-Universitaet Muenchen (LMU).
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Irina Solovei, Audrey?S. Wang, Katharina Thanisch, Christine?S. Schmidt, Stefan Krebs, Monika Zwerger, Tatiana?V. Cohen, Didier Devys, Roland Foisner, Leo Peichl, Harald Herrmann, Helmut Blum, Dieter Engelkamp, Colin?L. Stewart, Heinrich Leonhardt, Boris Joffe. LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation. Cell, 2013; 152 (3): 584 DOI: 10.1016/j.cell.2013.01.009
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
A week after Conference USA got its final realignment for 2013 together, FIU was able to announce a football schedule that opens Aug. 31 at Maryland and closes Nov. 30 at FAU.
In between, FIU hosts Central Florida on Sept. 7 and Bethune-Cookman on Sept. 14 in non-conference games. Their non-conference schedule ends with a trip to Sugar Bowl-champion Louisville, Sept. 21.
FIU?s in C-USA?s East Division with FAU and Middle Tennessee State, both of which will leave the Sun Belt with FIU and North Texas this summer; Marshall; Southern Mississippi; East Carolina; and Alabama-Birmingham. Games against each of the other East schools and two games against the West Division, the Oct. 26 Louisiana Tech home game and a Nov. 16 road game at UTEP, comprise FIU?s conference schedule.
The Panthers open conference play Oct. 5 at Southern Mississippi. After that, there?s a run of home conference games against Alabama-Birmingham, Louisiana Tech and East Carolina. The Panthers fourth and last home conference game is against Marshall, Nov. 23.
The closing game, the Shula Bowl against FAU, has slowly been brought back from limbo. First, it was to be suspended indefinitely because FIU was leaving FAU in the Sun Belt Conference. Then, the game got put on hiatus for only 2013 once FAU accepted the invitation from Conference USA. Once FAU and Middle decided to leave the Sun Belt in 2013 instead of 2014, the game got its late season place back on both schedules.
Jan. 30, 2013 ? Humans alone were responsible for the demise of Australia's iconic extinct native predator, the Tasmanian Tiger or thylacine, a new study led by the University of Adelaide has concluded.
Using a new population modelling approach, the study contradicts the widespread belief that disease must have been a factor in the thylacine's extinction.
The thylacine was a unique marsupial carnivore found throughout most of Tasmania before European settlement in 1803. Between 1886 and 1909, the Tasmanian government encouraged people to hunt thylacines and paid bounties on over 2000 thylacine carcasses. Only a handful of animals were located after the bounty was lifted and the last known thylacine was captured from the wild in 1933.
"Many people, however, believe that bounty hunting alone could not have driven the thylacine extinct and therefore claim that an unknown disease epidemic must have been responsible," says the project leader, Research Associate Dr Thomas Prowse, School of Earth and Environmental Sciences and the Environment Institute.
"We tested this claim by developing a 'metamodel' -- a network of linked species models -- that evaluated whether the combined impacts of Europeans could have exterminated the thylacine, without any disease."
The mathematical models used by conservation biologists to simulate the fate of threatened species under different management strategies (called population viability analysis or PVA) traditionally neglect important interactions between species. The researchers designed a new approach to PVA that included species interactions.
"The new model simulated the directs effects of bounty hunting and habitat loss and, importantly, also considered the indirect effects of a reduction in the thylacine's prey (kangaroos and wallabies) due to human harvesting and competition from millions of introduced sheep," Dr Prowse says.
"We found we could simulate the thylacine extinction, including the observed rapid population crash after 1905, without the need to invoke a mystery disease.
"We showed that the negative impacts of European settlement were powerful enough that, even without any disease epidemic, the species couldn't escape extinction."
The study 'No need for disease: testing extinction hypotheses for the thylacine using multi-species metamodels', which also involved Professors Corey Bradshaw and Barry Brook from the University of Adelaide's Environment Institute, Professor Chris Johnson from the University of Tasmania, and Dr Bob Lacy, Chicago Zoological Society, has been published online in the Journal of Animal Ecology.
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The above story is reprinted from materials provided by University of Adelaide.
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Journal Reference:
Thomas A. A. Prowse, Christopher N. Johnson, Robert C. Lacy, Corey J. A. Bradshaw, John P. Pollak, Michael J. Watts, Barry W. Brook. No need for disease: testing extinction hypotheses for the thylacine using multi-species metamodels. Journal of Animal Ecology, 2013; DOI: 10.1111/1365-2656.12029
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
LONDON (AP) -David Beckham will join Paris Saint-Germain on Thursday, opting for a move to France after mulling over lucrative offers from around the world since leaving the Los Angeles Galaxy.
The 37-year-old Beckham was to undergo a medical examination in the French capital before being officially presented as PSG's latest recruit, a person familiar with the situation told The Associated Press. The person spoke on condition of anonymity because the deal has not yet been completed.
PSG would only confirm that a new a player would be attending a news conference at 1600 GMT on Thursday.
PSG's Qatari-owners have invested more than $300 million in players since buying the club in 2011. But Beckham was available on a free transfer after he ended his six-year stint in the United States with a second MLS Cup title last month.
At PSG, Beckham will be hoping to win a league title in a fourth country, having already enjoyed success at Manchester United and Real Madrid in Europe before moving to Major League Soccer.
Beckham had been close to joining PSG last January but rejected a deal worth about $12 million per year to stay in California for one more season.
Now, though, Beckham and his family have moved back to London, which is a short flight or train ride from Paris.
Beckham made 115 appearances for England, a record for a player other than a goalkeeper.
? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Beckham to sign with PSG
??David Beckham will join Paris Saint-Germain on Thursday, opting for a move to France after mulling over lucrative offers from around the world since leaving the Los Angeles Galaxy.
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Today's MacUpdate Promo offers 55% savings on Boxshot Ultimate 4.0.20. "Boxshot is the ultimate tool kit for creating 3D models of software boxes, CDs, DVDs, mugs, cans, bags, and more! With over 50 highly customizable objects, you can do professional-quality design work right from your Mac."
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Tuesday Highlights: In the span of about 24 hours, the 128GB iPad went from rumor to reality as Apple made the official announcement today, pricing the new tablet at $799 for WiFi, $929 cellular; reports in our Apple/Macintosh, Hardware/Software, and Op/Ed sections including opinion that it should be called the "iPad Pro"; Giz lists 9 professions where the 128GB model should excel; others note that it is Apple's response to Microsoft's Surface Pro, but about $200 cheaper, and speaking of the Surface Pro, you'll only have 83GB free on the 128GB model, that's 45GB for Windows 8, pre-installed apps; CNBC explains the reasons behind Apple's rapid and drastic stock drop; Samsung pleads with Japan court to dismiss Apple's appeal and conclude the case; Fortune on Goldman Sach's big Apple bond deal; Robin Harris at ZDNet ponders whether Jony Ive is killing the Mac; Microsoft releases Office 2013 as a subscription service for $100/year, Mac version AWOL, but said to be on way; another round of quick fixes for common Mac problems from Mactuts+; Amsys has a second installment on client security with FileVault; IGN analysis of what are the biggest challenges facing gaming on the Mac, including price, upgrades, compatibility; in the enterprise, iPhone, Adroid produce happier employees and higher profits; it's coming, no really, the cheaper iPhone 5; Fast Co Design article on 26 Apple designs that never made it; pictures of purported iPad 5 casing hit the web, is a bigger iPad mini, as expected, more in our Hardware/Software section where you'll also find the newest of Apple's granted patents, and there's a lot of them including motion based payments, smart bikes, zooming on touch display, among others; here's a review of Intel's 335 240GB SSD.
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News
"Peak Mac ? Will Apple ever sell 5 million Macs in a quarter again?"?9 to 5 Mac?1:25 PM
"iWork Isn't Dead; Apple Hiring Engineer To Make Numbers App Better"?Apple Bitch?2:55 PM
"Is Jony Ive killing the Mac? Even as eye candy has been added to the Mac interface, basic functionality critical to data integrity and reliable operation have been subtracted. Is this Apple's design chief Jony Ive's fault?"?ZDNet?8:06 AM
"Peak Mac? Was 2012 a one-off year of treading water for Apple's Mac business? Or has the Mac peaked for good?"?SplatF?7:41 PM
"iPhone users take legal action against Google: Tech giant faces group privacy claim after it allegedly sidestepped Apple security settings."?Guardian News & Media?9:14 PM
"Microsoft Office 2013 Now Available, New Mac Version Still Missing in Action"?Mac|Life?9:29 AM
AppleCare/Troubleshooting
"Fix incorrect document associations in OS X: If opening documents launches the wrong program, or if you have repeated entries in the OS X Open With menu, then there is a quick solution that can fix the issue."?CNET Reviews?5:10 PM
Reviews/How-To/Tips
"Mac Gems: Trickster tracks your recently used items"?Macworld?8:19 AM
"5 More Quick Fixes to Common Mac Problems"?Mactuts+?8:10 AM
"How to quickly change audio output in OS X: If you need to switch audio interfaces, you can do so quickly from the OS X menu bar."?MacFixIt?7:41 PM
"Client Security Part 2 ? FileVault 2"?Amsys?9:00 AM
"Master The Option Key In The OS X Menu Bar [OS X Tips]?Cult of Mac?8:29 AM
"Scrub through tracks in iTunes 11 with two-finger swipe"?Mac OS X Hints?9:52 AM
"Control Mac Screen Brightness with Shady"?ResExcellence?7:51 AM
"Accordance Quicktip - Amplifying from the Library"?Accordance?10:29 AM
"The Easier Way To Manage Your Mac's App Window Clutter Is An Absolute Snap Tool"?Mac 360?7:58 AM
"Are You Tired Of The Typical Todo Apps And Task Schedulers? Daily Routine Thinks Different"?Mac 360?7:58 AM
"This Mac App I Want To Like Does Something I Need To Do But I Don't Like How It Does It"?Mac 360?7:58 AM
Op/Ed
"Seven 'must have' apps for your new Mac"?ZDNet?9:41 AM
"Mac Gaming's Biggest Challenges: Price, upgrades, and compatibility still haunt Apple's rigs."?IGN?9:36 AM
"Use Your Mac as a WiFi Hotspot, Make a Mountain Lion Recovery Disk, and More Mac News"?Low End Mac?9:29 AM
Press Releases
"The Dark Reef is an underwater action/adventure game. It's also a new take on video games, with weekly updates continuing a fully immersive story. Deep in the Pacific Ocean, a secret military operation has uncovered something sinister. And the international research station 'Dark Reef' is in its path! It's up to you to protect the station and its inhabitants while they race to unravel the origin and secrets of this mysterious new foe. Each week, a new episode will be released to subscribers, continuing that month's chapter in the story."?The Dark Reef?5:04 PM
"Open Source Edition of LiveCode"?KickStarter?4:25 PM
"Audiozue Is a Menubar App That Controls Music, Shows Your Trending Songs, and More"?Lifehacker?8:07 AM
"Hexius Has Arrived on the Mac App Store!"?prMac?11:14 AM
"iWeb Replacement App To Be Unveiled at Macworld 2013"?prMac?7:48 AM
"Dolly Drive to launch Space Virtual Storage at Macworld/iWorld2013"?prMac?7:48 AM
"Pixeljam Releases Potatoman Seeks the Troof in the Mac App Store"?prMac?7:48 AM
"Apple to sell 128GB models of its fourth-generation iPad with Retina display from February 5"?The Next Web?8:06 AM
"Apple iPad jumps to 128GB, starting at $799"?CNET News?8:21 AM
"128 GB Tablets to Hit Market"?Forbes?3:56 PM
"128GB iPad: from myth to reality in 24 hours/Apple has announced it's expanding its existing line of fourth-generation iPads."?Ars Technica?8:25 AM
"So that 128GB iPad? It's real, and it's available from Apple on Feb. 5"?GigaOM?8:29 AM
"Apple announces 128GB iPad"?Macworld?8:50 AM
"Apple dishes out 128GB iPad; available early February"?ZDNet?9:40 AM
"Slightly Smaller Apple TV 3,2 (A1469) Contains A5X SoC, BCM4334 Combo"?AnandTech?6:53 PM
"FCC filing reveals Apple TV model A1469 with slightly smaller dimensions"?Engadget?5:09 PM
"Slightly smaller Apple TV revealed by FCC filing"?The Verge?5:07 PM
"New Apple TV 3,2 to be half centimeter smaller, can now fit in your mouth"?9 to 5 Mac?5:08 PM
"FCC Documents Reveal A Smaller, More Powerful Apple TV Is Coming Soon"?TechCrunch?6:55 PM
"Smaller Apple TV box hinted at in FCC filing"?CNET News?6:54 PM
"Nearly 300 million devices now running iOS 6: Apple's SVP of Worldwide Marketing Phil Schiller announces new figures as iOS 6.1 is released"?Macworld UK?7:57 AM
"Apple says iOS 6 is now on 300 million devices as it rolls out v6.1"?Digital Trends?8:18 AM
"Apple Reportedly Chops Q1 9.7-Inch Ipad Orders In Half As Consumers Clamor For Ipad Mini"?BGR?11:34 AM
"Leaked Rear Panel Images Suggest The iPad 5 Will Look A Lot Like The iPad mini"?App Advice?8:08 AM
"Purported 'iPad 5' Back Plate Surfaces With Looks Akin To iPad Mini, Could Launch This March ? [Photos]?RazorianFly?8:07 AM
"Apple's Next iPad Could Sport A Slimmer Shell, Take A Page From The iPad Mini Playbook"?TechCrunch?10:29 AM
"Rumor: Amazing iPad 5 Component Pictures Appear"?AppleBitch?7:59 AM
"First iPad 5 Spy Photos Appear"?Tapscape?7:59 AM
"Taiwan market: Apple iPad mini far outsells iPad 4"?DigiTimes?7:56 AM
"LG Display sees decreased capacity utilization due to Apple order cuts"?DigiTimes?7:57 AM
"Apple trademarks design of its retail stores"?Reuters?9:07 PM
"Apple granted U.S. trademark for its retail store design"?Los Angeles Times [Paid Membership Required]?6:54 PM
"iOS 6.1: New Lockscreen Music Controls"?MacTrast?8:02 AM
"About the new 'Reset Advertising Identifier' button in iOS 6.1"?ZDNet?9:41 AM
"Whats New in iOS 6.1: Some Features, Lots of Security"?FairerPlatform?7:59 AM
"Apple TV Update - 5.2 w/ Bluetooth Keyboard Support (Video)"?Insanely Great Mac?8:49 AM
Granted Apple Patents
"Apple Wins 48 Patents Covering the iPhone 5's Integrated Touch Display, Apple's Zoom Feature & Electromagnetic Induction"?Patently Apple?9:07 AM
"Apple Wins iWallet Patent for Motion based Payment System"?Patently Apple?7:50 AM
"Apple Granted a Patent for an Intriguing Smart Bike System"?Patently Apple?7:50 AM
"Apple Granted 4 Design Patents Covering the iPod Touch & More"?Patently Apple?7:50 AM
"Apple granted patent involving zooming on a touch-screen display"?AppleDailyReport?9:03 AM
"Apple's new integrated touch screen patent mentions phones, media players AND personal computers"?AppleDailyReport?8:49 AM
"Apple patent involves group formation using anonymous broadcast information"?AppleDailyReport?8:58 AM
Price Trackers/Deals
"AstroWings3 Plus : ICARUS For iPhone and iPad Is Temporarily Available For Free (Normally $1.99)"?Apple Sliced?8:23 AM
"File Manager Pro App For iPhone and iPad Is Free Right Now (Previously $4.99)"?Apple Sliced?8:23 AM
"Stickman Ski Racer For iPhone and iPad Is Free Today (Was $0.99)"?Apple Sliced?8:23 AM
"15" MacBook Pro Prices & Sales"?MacPrices?7:50 AM
"13" MacBook Pro Prices & Sales"?MacPrices?7:50 AM
"MacBook Air Prices & Sales"?MacPrices?7:50 AM
"Apple refurbs: save up to $850 on Mac Pro"?MacNN?3:58 PM
"PadGadget Daily App Deal ? 8 iPad Apps on Sale"?PadGadget?8:09 AM
Deal Brothers Daily Deal: Get a Docking Station for your MacBook Air for $46
"Rant of the day: Android hate and Apple love"?Seattle Times?9:13 PM
"Remains of the Day: Trust fall"?Macworld?7:12 PM
"Cassandra -Wednesday Review: The Week in Full Swing"?eXtensions?6:45 PM
"Low Cost iPhone Rumors Simply Make No Sense"?Apple'n'Apps?4:01 PM
"Apple's Ups And Downs Are A Classic Study In Momentum Investing"?Forbes?3:58 PM
"Tim Cook Needs Eureka Moment To Get Apple Back Above $700"?Forbes?3:58 PM
"The Macalope Daily: Backlash"?Macworld?10:37 AM
"Conspiracy Theory: Did Apple And Google Agree To Split The Smart Phone Market?"?Mac 360?10:28 AM
"Leaving the iPhone: How Windows Phone 8 Stacks Up"?Tech.pinions?9:46 AM
"Apple vs. Amazon: Two Different Paths to Success" [Video Report]?Bloomberg?9:43 AM
"I fought the cord, and the cord won"?Macworld?9:03 AM
"Why on Earth would anyone want a $1,000 iPad? Is it overkill? Or just enough to get by? The answer depends on the user."?Ars Technica?5:02 PM
"Apple'S 128Gb Ipad Shows The World Exactly What Apple Does Best"?BGR?3:56 PM
"Why A 128GB iPad? Call It The iPad Pro [Opinion]?Cult of Mac?10:37 AM
"9 People Who Actually Need a 128GB iPad"?Gizmodo?9:43 AM
"For $200 less, the 128GB iPad is more appealing than Microsoft's Surface Pro"?ZDNet?9:39 AM
"Apple Produces A New iPad But No Excitement"?Forbes?9:02 AM
"The 128GB iPad Is Real, It's Here, and It's Almost Definitely Not For You"?Gizmodo?8:27 AM
"Low-cost iPhone will be like a plastic iPhone 5, claims story"?CNET News?8:21 AM
"Budget iPhone design to be a mix of iPhone 5, iPod Touch and iPod Classic, report claims"?Digital Trends?8:18 AM
"Steve Jobs biopic will be must-see for techies: Apple chief flick will fuel debate, nostalgia; despite inaccuracies"?MarketWatch?8:18 AM
"Jobs Movie Reviews Range from Good to Passable to Poor"?FairerPlatform?7:59 AM
Non-Apple
"Can you ever really delete yourself from the Internet?"?VentureBeat?5:03 PM
"And the 32 GB Surface Pro Will Have Just Enough Storage to Display the Start-Up Screen"?AllThingsD?5:02 PM
"Microsoft's Surface Pro to ship with as little as 36% of advertised storage available to users"?AppleInsider?5:02 PM
"On day Apple announces 128GB iPad, Microsoft admits that Surface Pro ships with 83GB free"?9 to 5 Mac?3:58 PM
"Report: 128GB Surface Pro Only Has 83GB Free for Users"?DailyTech?8:28 AM
"Why Microsoft's Office 2013 Subscription Model Will Flop"?PC Magazine?11:17 AM
"Microsoft Office 2013 review: Designed for tablets, but great for everyone" ["The bad: The $100-a-year subscription will be hard for many people to swallow. The upgraded apps are not available for Mac at this time, and won't be for 12 to 18 months."]?CNET Reviews?9:36 AM
"Office 2013 Is a Big Improvement, but Needs Polish"?Mashable?8:30 AM
"Review: Microsoft Office 365 Home Premium Edition hopes to be at your service"?Ars Technica?8:28 AM
"Microsoft Office 2013 is here: Hands-on impressions and buying advice"?PCWorld?8:28 AM
"Most Popular iPad Keyboard: Logitech Ultrathin Keyboard Cover"?Lifehacker?4:57 PM
"Top Tweaks For iPhone And iPad That Don't Require A Jailbreak"?Redmond Pie?1:26 PM
"After Being Removed For Porn, Photo-Sharing App 500px Is Back In Apple's App Store"?Business Insider?11:16 AM
"The New Office Is Here; Those Pesky iOS Apps Aren't"?AllThingsD?11:15 AM
"Macworld Live returns"?Macworld?11:14 AM
"500px Returns to the iOS App Store, Now Rated 17+"?Daring Fireball?4:26 PM
"500px Returns To The iOS App Store, With Mature Content Warning And Photo Reporting Button"?TechCrunch?11:14 AM
"Going to Macworld/iWorld? Come see Jacqui talk?twice: Ars' Apple Editor is doing Tech Talk on January 31 and a panel on February 1."?Ars Technica?10:40 AM
"Little Snitch sale, Yelp, 9GAG, USPS Mobile, Notabli, price drops, and more"?9 to 5 Mac?9:36 AM
"PadGadget Photobooth ? Check Out These Great Photography Magazines"?PadGadget?9:29 AM
"The Best Apps for New Parents"?Mashable?9:29 AM
"Macworld/iWorld 2013: MMT to reveal 'the future of mobile monitors'"?AppleTell?9:29 AM
"We're *This Close* To An iPhone 5 Jailbreak ? And It May Arrive As Soon As Sunday"?TechCrunch?8:59 AM
"Google Drive iOS update adds support for multiple photo/video uploads and more"?Digital Trends?8:18 AM
"Google Drive For iOS Gets Multiple Photo/Video Upload And Other Enhancements"?App Advice?8:08 AM
"Google updates Google Drive app"?AppleTell?8:06 AM
"Visual Voicemail on iPhone 5 now available for 4G EE customers"?Macworld UK?7:57 AM
"Qihoo Gets Double Dose Of Bad News As Apple Cuts Its iOS Apps And It Receives Unfair Competition Warning"?TechCrunch?7:57 AM
"LexisNexis Releases New Research, Litigation and Practical Guidance Tools Expanding its Comprehensive Portfolio of Legal Solutions"?Business Wire?7:49 AM
"THX Launches Its First Mobile iOS App to Help Consumers Properly Adjust and Get the Most from Their TV, Projector and Speakers"?Business Wire?7:49 AM
"Massive Dynamics Announces Completion of the First Production Run of the iPhone 5??Battery Pack"?Business Wire?7:49 AM
"ChordLab HD 3.0 Released"?prMac?7:49 AM
"Timeline: Minimalist Project Management v1.0 released for the iPad"?prMac?7:49 AM
"iPad Essay App Teaches How To Write Papers In Middle School"?prMac?7:48 AM
"Night Whisper Lane Scenario 2: Boss Rush Mode is Out Now"?prMac?7:48 AM
"New Microsoft Office: in the cloud or traditional software/Microsoft is expected to launch Tuesday its newest version of Office, which is available as a subscription ? another step in the company's evolution into a devices-and-services company."?Seattle Times?8:19 AM
"Microsoft's Cloud-Friendly Office 365 Launches"?Wired?8:43 AM
"Office 2013 goes on sale in Microsoft's UK store: The Inquirer (http://s.tt/1z5st)"?The Inquirer?8:13 AM
"Microsoft wants you to pay $100 a year for Office"?CNNMoney?8:16 AM
"Office 2013 available now: Microsoft ditches DVDs in push for cloud subscriptions"?The Verge?8:16 AM
"Microsoft won't deliver Office 365 updates for new business users until February"?ZDNet?11:04 AM
"Microsoft launches new Office for consumers"?Reuters?3:34 PM
"Microsoft pushes subscription model for Office 2013: Available for download beginning today, Office 2013 comes in a wide variety of versions. But Microsoft is hoping that you'll skip the one-time fee for a subscription model that delivers lots of updates to come."?CNET Reviews?8:15 AM
"Office boss: Within 10 years, every customer will subscribe/Kurt DelBene says that the software giant's push into services will lead to more and more customers opting for subscriptions to it its productivity application. But the transition from buying software to renting it will take as long as a decade."?CNET News?8:15 AM
"Microsoft (NASDAQ:MSFT) and Dell Inc. (NASDAQ:DELL) Forming a Formidable Union"?The Point Daily?8:09 AM
"Popularity of Google Chrome-Based Laptops Impede Windows 8 Sales"?24/7 Wall St.?7:45 AM
"Google exposes HP printers to attack"?Fudzilla?7:37 AM
"HP is jumping on the Google Chromebook bandwagon"?Bangkok Post?2:25 PM
"HP lining up Pavilion Chromebook: New device, leaked temporarily on HP webiste, will Reportedly feature 14-inch display"?Techworld?7:37 AM
"Analysis: Dell LBO talks reveal other leverage options"?Reuters?2:18 PM
"Reports: Is HP Prepping a New Chromebook?"?The VAR Guy?7:36 AM
"Microsoft's Role a Sticking Point in Dell Buyout Talks"?WSJ.com [Paid Membership Required]?3:36 PM
"Microsoft wants influence over privatized Dell, Reports WSJ"?The Verge?3:34 PM
"Dell has four different mobile device management (MDM) products. What's their strategy here?"?Brian Madden?7:35 AM
"Dell XPS 13 ultrabook with high-res display due next week: Dell's XPS 13 ultrabook finally gets the high-resolution display the design deserves."?CNET News?4:00 PM
"Dell Inc Stock Upgraded (DELL)"?TheStreet?7:34 AM
"IBM Declares Quarterly DiVidend of $0.85 (IBM)"?JAGSReport?3:31 PM
"RIM works IBM conference"?Canada?3:32 PM
"IBM adds big data capabilities and Microsoft Office integration to Connections"?V3?7:59 AM
"IBM suggests how social business can work for healthcare, retail, gov't"?ZDNet?3:37 PM
"Q&A: IBM's GM of social business on C-level strategies, Microsoft, and Oracle"?ZDNet?7:59 AM
"Obama Cites Intel, Instagram As Examples Of Immigrant-Powered Companies"?Talking Points Memo?3:33 PM
"Intel promotes senior executives ahead of Otellini's exit"?The Inquirer?8:01 AM
"Intel Launches Celeron 927UE, 1020E and 1047UE Ivy Bridge CPUs"?Softpedia?7:53 AM
"Safaricom launches new smartphone in Africa with Intel Inside"?infoTECH?7:52 AM
"Nokia pours $250m into its VC business, grows China/Nokia Growth Partners has scored $250m in funding from Nokia and adds AMD China's president to its payroll, in order to grow business in the country."?ZDNet?7:47 AM
"Nokia invests $250m into venture capital business"?Mobile Magazine?7:47 AM
"Facebook, ARM, x86, and the data centre of tomorrow"?ITProPortal?7:46 AM
"Cisco Unified Access updates focus on addressing 'Internet of Things'"?ZDNet?7:51 AM
"Cisco Catalyst marries wired, wireless and SDN in one switch: Catalyst 3850 and 5760 WLAN controller offer consistent wireless and wired management, services through new programmable ASIC"?Network World?7:50 AM
"Unified Access is Cisco's Next-Gen Strategy"?Channelnomics?7:50 AM
"Cisco Finalizes Unified Access Strategy Lineup"?The VAR Guy?7:51 AM
"Cisco unveils hybrid wireless-wired network access kit"?V3?7:51 AM
"Oracle Wants Cloud Cake And Hardware Wins"?TechWeb News?8:53 AM
"Java Security Work Remains, Bug Hunter Says"?TechWeb News?8:54 AM
"Oracle Cloud Success Triggers Oracle-Derangement Syndrome"?Forbes?8:20 AM
"Three years later, has Oracle's Sun buy paid off? Cash flow has far exceeded purchase price, according to Oracle President Mark Hurd, but an investment researcher remains doubtful"?InfoWorld?3:35 PM
"Internet, social media least trusted industries for privacy: Google, Facebook, Yahoo, and AOL were just four of the tech companies missing from Ponemon's Top 20 list of the most trusted companies."?CNET News?1:22 PM
Finances
(Click heading for current Apple Stock price.)
Apple News
"Apple regains 'el numero uno' market-value crown: iPad reveal steals Microsoftian thunder on Office 365 day"?The Register?4:46 PM
"Facebook Gains on Apple in Wall Street Rating Race"?WSJ.com [Paid Membership Required]?4:47 PM
"From Apple to Where?" [Video Report]?CNBC?3:56 PM
"At Worst, Apple Is A $400 Stock"?Forbes?3:54 PM
"Who Sold Off Apple? One Fund Company's Multi-billion Dollar Dump"?Barron's?1:25 PM
"How Apple Gave Wall Street The Middle Finger"?Seeking Alpha?9:44 AM
"Apple dragging down hedge funds"?CNNMoney?8:19 AM
"Apple 'could be sued' for sitting on $137.1 billion cash, expert"?Macworld UK?7:57 AM
"Apple Supplier AMS Drops as Net Misses Estimates: Zurich Mover"?Bloomberg?8:18 AM
Industry News
"Stocks Close Mixed as Dow Hits 2007 High"?TheStreet?4:06 PM
"Yahoo, VMware, EMC drive down techs: Shares tumble on earnings results; Apple gains on new iPad news"?MarketWatch?4:08 PM
"Futures Slip as Traders Digest Data, Earnings"?FOXBusiness?8:58 AM
"Asia Markets: Asia stocks end mostly higher; Hong Kong lags/Asia markets rose Tuesday, with Japan stocks boosted by a solid rally in banks, although Hong Kong shares lagged behind, weighed by Industrial & Commercial Bank of China Ltd. after Goldman Sachs Group Inc. pared its stake in the lender."?MarketWatch?8:57 AM
"Europe Markets: Europe stocks key off Wall Street gains/Oil firms led European stocks higher on Tuesday, as oil prices topped $97 a barrel for the first time since mid-September, while encouraging German consumer-confidence data and solid U.S. earnings reports also lifted sentiment."?MarketWatch?3:38 PM